■ Interplay between a Foldamer Helix and a Macrocycle in a Foldarotaxane Architecture
   
   M. Gauthier, V. Koehler, C. Clavel, B. Kauffmann, I. Huc, Y. Ferrand and F. Coutrot
   Angew. Chem. Int. Ed. 2021, 60, 8380-8384.
   Evaluated as a hot paper and featured by a Cover Picture

■ Challenges and Opportunities in the Post‐Synthetic Modification of Interlocked Molecules
   
   P. Waelès, M. Gauthier and F. Coutrot
   Angew. Chem. Int. Ed. 2021, 60, 16778-16799
   featured by a frontispiece

► 2022

■ Association of Liquid-Assisted Grinding with Aging Accelerates the Inherently Slow Slipping-on of a Dibenzo-24-Crown-8 over the
   N-hydroxysuccinimide Ester of an Ammonium-Containing Thread
   
   B. Riss-Yaw, T. X. Métro, F. Lamaty and F. Coutrot
   RSC Advances, 2019, 9, 21587-21590

■ Weinreb Amide as Secondary Station for the DB24C8 in a Molecular Shuttle

   M. Gauthier and F. Coutrot
   Eur. J. Org. Chem. 2019, 21, 3391-3395

► 2019

■ The Importance of Length and flexibility of Macrocycle-Containing Molecular Translocator of Macrocycle for the Synthesis of Improbable
   [2]Rotaxanes   

   B. Riss-Yaw, C. Clavel, Ph. Laurent, P. Waelès and F. Coutrot   
   Chem. Eur. J. 2018, 24, 13659-13666

► 2018

■ How secondary and tertiary amide moieties are molecular stations for dibenzo-24-crown-8 in [2]rotaxane molecular shuttles ?   

   B. Riss-Yaw, J. Morin, C. Clavel and F. Coutrot   
   Molecules, 2017, 22, 2017

back cover

■ The relationship between the conformational degree of freedom of template-containing threads and slippage in the formation of [2]rotaxane building blocks   

   B. Riss-Yaw, C. Clavel, Ph. Laurent and F. Coutrot   
   Chem. Commun. 2017, 53, 10874-10877
   fetaured by a back cover

frontispiece

■ Distinguishing two Ammonium and a Triazolium Sites of Interactions in a Three-Station [2]Rotaxane Molecular Shuttle   

   P. Waelès, K. Fournel-Marotte and F. Coutrot   
   Chem. Eur. J. 2017, 23, 11529-11539
   featured by a frontispiece

■ Moving into another dimension 

   K. Fournel-Marotte and F. Coutrot   
   Nat. Chem. 2017, 9, 105-106

► 2017

highlighted in Atlas of Science (2016, September 23, 2016)
Introduced by W. R. Browne,A. Woolley, and D.-H. Qu, ChemPhysChem 2016, 17, 1713-1714

highlighted in Atlas of Science (2016, September 13, 2016)

featured by a cover illustration (Chem. Eur. J. 2016, 22, 6987)

featured by a cover illustration (Chem. Eur. J. 2016, 22, 8706)
highlighted in Atlas of Science (2016, October 11, 2016)

■ Active Esters as Pseudo-Stoppers for Slippage Synthesis of [2]Pseudorotaxane Building-Blocks: A Straightforward Route to Multi-Interlocked Molecular Machines

   T. Legigan, B. Riss-Yaw, C. Clavel and F. Coutrot
   Chem. Eur. J. 2016, 22, 8835-8847

■ Reverse Anomeric Effect in Large-Amplitude Pyridinium Amide-containing Mannosyl[2]Rotaxane Molecular Shuttles   

   Benjamin Riss-Yaw, Philip Waelès and Frédéric Coutrot   
   Chem. Phys. Chem. 2016, 17, 1860-1869.

■ Synthesis of a pH-Sensitive Hetero[4]Rotaxane Molecular Machine that Combines [c2]Daisy and [2]Rotaxane Arrangements   
   Philip Waelès, Benjamin Riss-Yaw and Frédéric Coutrot     
   Chem. Eur. J. 2016, 22, 6837-6845.
   Evaluated as a hot paper

► 2016

highlighted in ChemInform, Volume 46, Issue 48, December, 2015: doi:10.1002/chin.201548235

■ Synthesis of Triazolium-Based Mono- and Tris-branched [1]Rotaxanes Using a Molecular Transporter of Dibenzo-24-Crown-8   

   Philip Waelès, Caroline Clavel, Karine Fournel-Marotte and Frédéric Coutrot   
   Chem. Sci., 2015, 6, 4828-4836.

■ A Focus on Triazolium as a Multipurpose Molecular Station for pH-Sensitive Interlocked  Crown Ether-Based Molecular Machines  

   Frédéric Coutrot   
   ChemistryOpen, 2015, 4, 556-576.

■ Recent Advances in the Chemical Synthesis of Lasso Molecular Switches

   Frédéric Coutrot   
   Springer International Publishing Switzerland   
   C. Joachim and G. Rapenne (Eds.)Single Molecular Machines and Motors,   
   Series: Advances in Atom and Single Molecule Machines 2015, 35-64.

► 2015

■ A Strategy Utilizing a Recyclable Transporter of Macrocycle for the Efficient Synthesis of a Triazolium-Based [2]Rotaxane

   Sovy Chao, Camille Romuald, Karine Fournel-Marotte, Caroline Clavel, Frédéric Coutrot
   Angew. Chem. Int. Ed. 2014, 53, 6914 –6919.

► 2014

Highlighted by Organic Letters as the most cited articles for the journal that were published within the last three year (February-September 2011)

► 2008

■ A Very Efficient Synthesis of a Mannosyl Orthoester [2]Rotaxane and Mannosidic [2]Rotaxanes

   Frédéric Coutrot, Eric Busseron, Jean-Louis Montero     
   Org. Lett. 2008, 10, 5, 753-756.

■ A New Glycorotaxane Molecular Machine Based on an Anilinium and a Triazolium station

   Frédéric Coutrot, Eric Busseron
   Chem. Eur. J. 2008, 14, 16, 4784-4787.







[published as "of interest"]

■ A New pH Switchable Dimannosyl [c2]Daisy Chain Molecular Machine

   Frédéric Coutrot, Camille Romuald, Eric Busseron
   Org. Lett. 2008, 10, 17, 3741-3744.







[For highlights of this paper see: pH changes trigger a single-molecule rotaxane, Sally Peng Li, Noteworthy Chemistry, October 20, 2008; Новости химической науки (in Russian), October 27, 2008]

■ A pH-Sensitive Peptide-Containing Lasso Molecular Switch

   Caroline Clavel, Karine Fournel-Marotte, Frédéric Coutrot
   invited paper for a special issue entitled Rotaxanes, Molecules, 2013, 18, 11553-11575.

■ N-Benzyltriazolium as both Molecular Station and Barrier in [2]Rotaxane Molecular Machines

   Eric Busseron and Frédéric Coutrot
   J. Org. Chem. 2013, 78, 4099-4106.

[Featured on the front cover of Chem. Eur. J. 2013, Volume 19, issue 9]

■ Straightforward Synthesis of a Double-Lasso Macrocycle from a non-Symmetrical [c2]-Daisy Chain

   Camille Romuald, Guillaume Cazals, Christine Enjalbal and Frédéric Coutrot
   Org. Lett. 2013, 15, 1, 184-187.

■ A pH-Sensitive Lasso-based Rotaxane Molecular Switch

   Caroline Clavel, Camille Romuald, Emile Brabet and Frédéric Coutrot
   Chem. Eur. J. 2013, 19, 2982-2989.

► 2012

■ Rotaxane-Based Propeptides: Protection and Enzymatic Release of a Bioactive Pentapeptide

   Anthony Fernandes, Aurélien Vitérisi, Frédéric Coutrot, Stéphanie Potok, David Leigh, Vincent Aucagne, Sébatien Papot
   Angew. Chem. Int. Ed. 2009, 48, 35, 6443-6447, Angew. Chem. 2009, 121, 35, 6565-6569.

■ Tightening or Loosening a pH-sensitive double-Lasso Molecular Machine Readily Synthesized from an Ends-Activated [c2]Daisy Chain

   Camille Romuald, Ana Arda-Freire, Caroline Clavel, Jesus Jimenez-Barbero and Frédéric Coutrot
   Chem. Sci. 2012, 3, 1851-1857.

■ Combining Coordination Chemistry and Catalysis to Tie a Knot in an Active Metal Template Strategy

   Camille Romuald and Frédéric Coutrot
   Angew. Chem., Int. Ed. 2012, 51, 2544-2545.

► 2013

■ Very Contracted to Extended co-Conformations with or without Oscillations in Two-and Three-Station[c2]Daisy Chains

   Camille Romuald, Eric Busseron and Frédéric Coutrot
   J. Org. Chem. 2010, 75, 6516-6531.

■ Bistable or Oscillating State Depending on Station and Temperature in Three-Station Glycorotaxane Molecular Machines

   Eric Busseron, Camille Romuald and Frédéric Coutrot
   Chem. Eur. J. 2010, 16, 10062-10073.

► 2010

[Featured on the front cover of Chem. Eur. J. 2009, Volume 15, issue 21]

► 2009

■ Controlling the Chair Conformation of a Mannopyranose in a Large-Amplitude [2]Rotaxane Molecular Machine

   Frédéric Coutrot, Eric Busseron
   Chem. Eur. J. 2009, 15, 21, 5186-5190

Publications

■ New Glycosyl a-Hydroxyesters as Key Intermediates in a convenient route to Glycosyl alpha-Aminoester Chirons     

   Frédéric Coutrot, Claude Grison, and Philippe Coutrot     
   Tetrahedron, 2002, 58, 2735-2741.

► 2001

[Featured on the front cover of Comptes Rendus Chimie, 2004, Volume 7, Issue 1, Janvier 2004]

■ A Model for Double Asymmetric Induction in the Stereocontrolled Reduction of Glycosyl alpha-Ketoesters with Oxazaborolidines   

   Harb, W., Ruiz-Lopez, M. F., Coutrot, F.; Grison, C., Coutrot, P.     
  J. Am. Chem. Soc. 2004, 126, 22, 6996-7008.

■ New efficient synthesis of a-hydroxyesters from carbonyl compounds via alpha-chloroglycidic esters   
   
   Claude Grison, Frédéric Coutrot, Corinne Comoy, Claude Lemilbeau, Philippe Coutrot     
   Tetrahedron Lett., 2000, 41, 34, 6571-6574.     [For a highlight of this paper see: cheminform 2000, 43, 084]

■ A route to new galactosyl peptides: application to the synthesis of a galactosyl pentapeptide analogue of leu-enkephalin
     
   Frédéric Coutrot, Claude Grison and Philippe Coutrot     
   Comptes Rendus Chimie, 2004, 7, 3-13.



                                       

► 2003

■ Lithiated anions derived from (alkenyl)pentamethyl phosphoric triamides: an accurate study of the carbanion formation mechanism
     
   Claude Grison, Antoine Thomas, Frédéric Coutrot and Philippe Coutrot     
   Journal of Organometallic Chemistry, 2004, 689, 9, 1530-1539.

■ Synthesis and Structural Study of a Fully protected alpha-C-galactosyl model dipeptide     

   Frédéric Coutrot, Michel Marraud, Bernard Maigret, Claude Grison, and Philippe Coutrot     
   Letters in Peptide Science, 2002, 8, 107-116.

■ Inclusion complexes of N-sulfamoyloxazolidinones with β-cyclodextrin

   Mekki Kadri, Rayenne Djemil, Mohamed Abdaoui, Jean-Yves Winum, Frédéric Coutrot and Jean-Louis Montero     
  Bioorganic & Medicinal Chemistry Letters, 2005, 15, 4, 889-894.

► 2002

► 2004

■ From reactants to Products via Simple Hydrogen Bonding Networks: Information Transmission in Chemical Reactions     

   Giuseppe Brancato, Frédéric Coutrot, David A. Leigh, Aden Murphy, Jenny K. Y. Wong, and Francesco Zerbetto     
   Proc. Natl. Acad. Sci. USA, 2002, 99, 8, 4967-4971.

■ A Novel Versatile Glycosyl a-Aminoacid Derivative for Glycopeptidic Chemistry
     
   Philippe Coutrot, Claude Grison, Frédéric Coutrot     
   Synlett, 1998, 393-395.

► 1998

■ New ketone homoenolate anion equivalents derived from (alkenyl)pentamethyl phosphoric triamides

   Claude Grison, Antoine Thomas, Frédéric Coutrot and Philippe Coutrot     
   Tetrahedron, 2003, 59, 12, 2101-2123.

► 2000

► 2005

■ Synthesis of New Glycosyl alpha-Aminoacid derivatives for Glycopeptide Chemistry 
   
   Claude Grison, Frédéric Coutrot, and Philippe Coutrot     
   Tetrahedron, 2001, 57, 6215-6227.     [For a highlight of this paper see: cheminform 2001, 43, 208]

■ Structure of epitopes recognized by the antibodies to a(181-192) peptides of neuronal nicotinic acetylcholine receptors: extrapolation to the
   struture of acetylcholine-binding domain       

   Skok M., Lykhmus E., Bobrovnik S., Tzartos S., Tsouloufis, T., Vanderesse, R., Coutrot F., Thong Cung M., Marraud M., Krikorian D., Sakarellos-
   Daitsiotis M.       
   J. Neuroimmunol. 2001, 121/1-2, 59-66.

■ 6,7-dideoxy-1,2:3,4-di-O-isopropylidene-7-[[(1S)-1-phenylethyl] amino] L-glycero-alpha-D-galacto-Octopyranuronate
     
   Frédéric Coutrot, Claude Grison, Philippe Coutrot, Loïc Toupet     
  Acta Cryst. 2001, E57, o519-o520.

■ Discrepancy Regarding the Dethreading of a DB24C8 Macrocycle through a Perfluorobutyl End in [2]Pseudorotaxanes
   
   M. Gauthier and F. Coutrot
   Eur. J. Org. Chem. 2022, e202101201

■ Weinreb Amide, Ketone and Amine as Potential and Competitive Secondary Molecular Stations for Dibenzo-24-Crown-8
   in [2]Rotaxane Molecular Shuttles
   
   M. Gauthier and F. Coutrot
   Chem. Eur. J. 2021, 27, 17576-17580
   Evaluated as a hot paper and featured by a Cover Picture

■ Post-Synthetic Macrocyclization of Rotaxane Building Blocks
   
   M. Gauthier, P. Waelès and F. Coutrot
   ChemPlusChem 2022, 87, e202100458

  featured by a frontispiece and a Cover picture

► 2021

■ Study of [2] and [3]Rotaxanes Obtained by Post-Synthetic Aminolysis of a Kinetically Stable Though Activated
   Carbonate-Containing Pseudorotaxane
   
   P. Waelès, M. Gauthier and F. Coutrot
   Eur. J. Org. Chem. 2022, e202101385

■ [3]Foldarotaxane-Mediated Synthesis of an Improbable [2]Rotaxane

V. Koehler, M. Gauthier, C. Yao, K. Fournel-Marotte, P. Waelès, B. Kauffmann, I. Huc, F. Coutrot and Y. Ferrand
Chem. Commun. 2022, 58, 8618-8621

featured by the inside front cover of the issue

Frédéric Coutrot

► 2023

■ An Interlocked Figure-of-Eight Molecular Shuttle
   
   M. Gauthier, K. Fournel-Marotte, C. Clavel, P. Waelès, P. Laurent and F. Coutrot
   Angew. Chem. Int. Ed. 2023, e202310643

   highlighted by D. Zhao and G. Yang in Synfacts 2023, 19, 1193

► 2024

■ A Foldaxane-based Supramolecular Muscle-Like Switch
   
   P. Waelès and F. Coutrot
   ChemistryOpen 2024, 13, e202400076

■ Cascading Macrocycle and Helix Motions in a Foldarotaxane Molecular Shuttle
   
   R. Hess, M. Brenet, H. Rajaonarivelo, M. Gauthier, V. Koehler, P. Waelès, I. Huc, Y. Ferrand and F. Coutrot
   Angew. Chem. Int. Ed. 2024, e202413977

  featured by the back cover of the issue