■ Interplay between a Foldamer Helix and a Macrocycle in a Foldarotaxane Architecture
   
   M. Gauthier, V. Koehler, C. Clavel, B. Kauffmann, I. Huc, Y. Ferrand and F. Coutrot
   Angew. Chem. Int. Ed. 2021, 60, 8380-8384.
   Evaluated as a hot paper and featured by a Cover Picture

■ Challenges and Opportunities in the Post‐Synthetic Modification of Interlocked Molecules
   
   P. Waelès, M. Gauthier and F. Coutrot
   Angew. Chem. Int. Ed. 2021, 60, 16778-16799
   featured by a frontispiece

► 2022

■ Association of Liquid-Assisted Grinding with Aging Accelerates the Inherently Slow Slipping-on of a Dibenzo-24-Crown-8 over the
   N-hydroxysuccinimide Ester of an Ammonium-Containing Thread
   
   B. Riss-Yaw, T. X. Métro, F. Lamaty and F. Coutrot
   RSC Advances, 2019, 9, 21587-21590

■ Weinreb Amide as Secondary Station for the DB24C8 in a Molecular Shuttle

   M. Gauthier and F. Coutrot
   Eur. J. Org. Chem. 2019, 21, 3391-3395

► 2019

■ The Importance of Length and flexibility of Macrocycle-Containing Molecular Translocator of Macrocycle for the Synthesis of Improbable
   [2]Rotaxanes   

   B. Riss-Yaw, C. Clavel, Ph. Laurent, P. Waelès and F. Coutrot   
   Chem. Eur. J. 2018, 24, 13659-13666

► 2018

■ How secondary and tertiary amide moieties are molecular stations for dibenzo-24-crown-8 in [2]rotaxane molecular shuttles ?   

   B. Riss-Yaw, J. Morin, C. Clavel and F. Coutrot   
   Molecules, 2017, 22, 2017

back cover

■ The relationship between the conformational degree of freedom of template-containing threads and slippage in the formation of [2]rotaxane building blocks   

   B. Riss-Yaw, C. Clavel, Ph. Laurent and F. Coutrot   
   Chem. Commun. 2017, 53, 10874-10877
   fetaured by a back cover

frontispiece

■ Distinguishing two Ammonium and a Triazolium Sites of Interactions in a Three-Station [2]Rotaxane Molecular Shuttle   

   P. Waelès, K. Fournel-Marotte and F. Coutrot   
   Chem. Eur. J. 2017, 23, 11529-11539
   featured by a frontispiece

■ Moving into another dimension 

   K. Fournel-Marotte and F. Coutrot   
   Nat. Chem. 2017, 9, 105-106

► 2017

highlighted in Atlas of Science (2016, September 23, 2016)
Introduced by W. R. Browne,A. Woolley, and D.-H. Qu, ChemPhysChem 2016, 17, 1713-1714

highlighted in Atlas of Science (2016, September 13, 2016)

featured by a cover illustration (Chem. Eur. J. 2016, 22, 6987)

featured by a cover illustration (Chem. Eur. J. 2016, 22, 8706)
highlighted in Atlas of Science (2016, October 11, 2016)

■ Active Esters as Pseudo-Stoppers for Slippage Synthesis of [2]Pseudorotaxane Building-Blocks: A Straightforward Route to Multi-Interlocked Molecular Machines

   T. Legigan, B. Riss-Yaw, C. Clavel and F. Coutrot
   Chem. Eur. J. 2016, 22, 8835-8847

■ Reverse Anomeric Effect in Large-Amplitude Pyridinium Amide-containing Mannosyl[2]Rotaxane Molecular Shuttles   

   Benjamin Riss-Yaw, Philip Waelès and Frédéric Coutrot   
   Chem. Phys. Chem. 2016, 17, 1860-1869.

■ Synthesis of a pH-Sensitive Hetero[4]Rotaxane Molecular Machine that Combines [c2]Daisy and [2]Rotaxane Arrangements   
   Philip Waelès, Benjamin Riss-Yaw and Frédéric Coutrot     
   Chem. Eur. J. 2016, 22, 6837-6845.
   Evaluated as a hot paper

► 2016

highlighted in ChemInform, Volume 46, Issue 48, December, 2015: doi:10.1002/chin.201548235

■ Synthesis of Triazolium-Based Mono- and Tris-branched [1]Rotaxanes Using a Molecular Transporter of Dibenzo-24-Crown-8   

   Philip Waelès, Caroline Clavel, Karine Fournel-Marotte and Frédéric Coutrot   
   Chem. Sci., 2015, 6, 4828-4836.

■ A Focus on Triazolium as a Multipurpose Molecular Station for pH-Sensitive Interlocked  Crown Ether-Based Molecular Machines  

   Frédéric Coutrot   
   ChemistryOpen, 2015, 4, 556-576.

■ Recent Advances in the Chemical Synthesis of Lasso Molecular Switches

   Frédéric Coutrot   
   Springer International Publishing Switzerland   
   C. Joachim and G. Rapenne (Eds.)Single Molecular Machines and Motors,   
   Series: Advances in Atom and Single Molecule Machines 2015, 35-64.

► 2015

■ A Strategy Utilizing a Recyclable Transporter of Macrocycle for the Efficient Synthesis of a Triazolium-Based [2]Rotaxane

   Sovy Chao, Camille Romuald, Karine Fournel-Marotte, Caroline Clavel, Frédéric Coutrot
   Angew. Chem. Int. Ed. 2014, 53, 6914 –6919.

► 2014

Highlighted by Organic Letters as the most cited articles for the journal that were published within the last three year (February-September 2011)

► 2008

■ A Very Efficient Synthesis of a Mannosyl Orthoester [2]Rotaxane and Mannosidic [2]Rotaxanes

   Frédéric Coutrot, Eric Busseron, Jean-Louis Montero     
   Org. Lett. 2008, 10, 5, 753-756.

■ A New Glycorotaxane Molecular Machine Based on an Anilinium and a Triazolium station

   Frédéric Coutrot, Eric Busseron
   Chem. Eur. J. 2008, 14, 16, 4784-4787.







[published as "of interest"]

■ A New pH Switchable Dimannosyl [c2]Daisy Chain Molecular Machine

   Frédéric Coutrot, Camille Romuald, Eric Busseron
   Org. Lett. 2008, 10, 17, 3741-3744.







[For highlights of this paper see: pH changes trigger a single-molecule rotaxane, Sally Peng Li, Noteworthy Chemistry, October 20, 2008; Новости химической науки (in Russian), October 27, 2008]

■ A pH-Sensitive Peptide-Containing Lasso Molecular Switch

   Caroline Clavel, Karine Fournel-Marotte, Frédéric Coutrot
   invited paper for a special issue entitled Rotaxanes, Molecules, 2013, 18, 11553-11575.

■ N-Benzyltriazolium as both Molecular Station and Barrier in [2]Rotaxane Molecular Machines

   Eric Busseron and Frédéric Coutrot
   J. Org. Chem. 2013, 78, 4099-4106.

[Featured on the front cover of Chem. Eur. J. 2013, Volume 19, issue 9]

■ Straightforward Synthesis of a Double-Lasso Macrocycle from a non-Symmetrical [c2]-Daisy Chain

   Camille Romuald, Guillaume Cazals, Christine Enjalbal and Frédéric Coutrot
   Org. Lett. 2013, 15, 1, 184-187.

■ A pH-Sensitive Lasso-based Rotaxane Molecular Switch

   Caroline Clavel, Camille Romuald, Emile Brabet and Frédéric Coutrot
   Chem. Eur. J. 2013, 19, 2982-2989.

► 2012

■ Rotaxane-Based Propeptides: Protection and Enzymatic Release of a Bioactive Pentapeptide

   Anthony Fernandes, Aurélien Vitérisi, Frédéric Coutrot, Stéphanie Potok, David Leigh, Vincent Aucagne, Sébatien Papot
   Angew. Chem. Int. Ed. 2009, 48, 35, 6443-6447, Angew. Chem. 2009, 121, 35, 6565-6569.

■ Tightening or Loosening a pH-sensitive double-Lasso Molecular Machine Readily Synthesized from an Ends-Activated [c2]Daisy Chain

   Camille Romuald, Ana Arda-Freire, Caroline Clavel, Jesus Jimenez-Barbero and Frédéric Coutrot
   Chem. Sci. 2012, 3, 1851-1857.

■ Combining Coordination Chemistry and Catalysis to Tie a Knot in an Active Metal Template Strategy

   Camille Romuald and Frédéric Coutrot
   Angew. Chem., Int. Ed. 2012, 51, 2544-2545.

► 2013

■ Very Contracted to Extended co-Conformations with or without Oscillations in Two-and Three-Station[c2]Daisy Chains

   Camille Romuald, Eric Busseron and Frédéric Coutrot
   J. Org. Chem. 2010, 75, 6516-6531.

■ Bistable or Oscillating State Depending on Station and Temperature in Three-Station Glycorotaxane Molecular Machines

   Eric Busseron, Camille Romuald and Frédéric Coutrot
   Chem. Eur. J. 2010, 16, 10062-10073.

► 2010

[Featured on the front cover of Chem. Eur. J. 2009, Volume 15, issue 21]

► 2009

■ Controlling the Chair Conformation of a Mannopyranose in a Large-Amplitude [2]Rotaxane Molecular Machine

   Frédéric Coutrot, Eric Busseron
   Chem. Eur. J. 2009, 15, 21, 5186-5190

Publications

■ New Glycosyl a-Hydroxyesters as Key Intermediates in a convenient route to Glycosyl alpha-Aminoester Chirons     

   Frédéric Coutrot, Claude Grison, and Philippe Coutrot     
   Tetrahedron, 2002, 58, 2735-2741.

► 2001

[Featured on the front cover of Comptes Rendus Chimie, 2004, Volume 7, Issue 1, Janvier 2004]

■ A Model for Double Asymmetric Induction in the Stereocontrolled Reduction of Glycosyl alpha-Ketoesters with Oxazaborolidines   

   Harb, W., Ruiz-Lopez, M. F., Coutrot, F.; Grison, C., Coutrot, P.     
  J. Am. Chem. Soc. 2004, 126, 22, 6996-7008.

■ New efficient synthesis of a-hydroxyesters from carbonyl compounds via alpha-chloroglycidic esters   
   
   Claude Grison, Frédéric Coutrot, Corinne Comoy, Claude Lemilbeau, Philippe Coutrot     
   Tetrahedron Lett., 2000, 41, 34, 6571-6574.     [For a highlight of this paper see: cheminform 2000, 43, 084]

■ A route to new galactosyl peptides: application to the synthesis of a galactosyl pentapeptide analogue of leu-enkephalin
     
   Frédéric Coutrot, Claude Grison and Philippe Coutrot     
   Comptes Rendus Chimie, 2004, 7, 3-13.



                                       

► 2003

■ Lithiated anions derived from (alkenyl)pentamethyl phosphoric triamides: an accurate study of the carbanion formation mechanism
     
   Claude Grison, Antoine Thomas, Frédéric Coutrot and Philippe Coutrot     
   Journal of Organometallic Chemistry, 2004, 689, 9, 1530-1539.

■ Synthesis and Structural Study of a Fully protected alpha-C-galactosyl model dipeptide     

   Frédéric Coutrot, Michel Marraud, Bernard Maigret, Claude Grison, and Philippe Coutrot     
   Letters in Peptide Science, 2002, 8, 107-116.

■ Inclusion complexes of N-sulfamoyloxazolidinones with β-cyclodextrin

   Mekki Kadri, Rayenne Djemil, Mohamed Abdaoui, Jean-Yves Winum, Frédéric Coutrot and Jean-Louis Montero     
  Bioorganic & Medicinal Chemistry Letters, 2005, 15, 4, 889-894.

► 2002

► 2004

■ From reactants to Products via Simple Hydrogen Bonding Networks: Information Transmission in Chemical Reactions     

   Giuseppe Brancato, Frédéric Coutrot, David A. Leigh, Aden Murphy, Jenny K. Y. Wong, and Francesco Zerbetto     
   Proc. Natl. Acad. Sci. USA, 2002, 99, 8, 4967-4971.

■ A Novel Versatile Glycosyl a-Aminoacid Derivative for Glycopeptidic Chemistry
     
   Philippe Coutrot, Claude Grison, Frédéric Coutrot     
   Synlett, 1998, 393-395.

► 1998

■ New ketone homoenolate anion equivalents derived from (alkenyl)pentamethyl phosphoric triamides

   Claude Grison, Antoine Thomas, Frédéric Coutrot and Philippe Coutrot     
   Tetrahedron, 2003, 59, 12, 2101-2123.

► 2000

► 2005

■ Synthesis of New Glycosyl alpha-Aminoacid derivatives for Glycopeptide Chemistry 
   
   Claude Grison, Frédéric Coutrot, and Philippe Coutrot     
   Tetrahedron, 2001, 57, 6215-6227.     [For a highlight of this paper see: cheminform 2001, 43, 208]

■ Structure of epitopes recognized by the antibodies to a(181-192) peptides of neuronal nicotinic acetylcholine receptors: extrapolation to the
   struture of acetylcholine-binding domain       

   Skok M., Lykhmus E., Bobrovnik S., Tzartos S., Tsouloufis, T., Vanderesse, R., Coutrot F., Thong Cung M., Marraud M., Krikorian D., Sakarellos-
   Daitsiotis M.       
   J. Neuroimmunol. 2001, 121/1-2, 59-66.

■ 6,7-dideoxy-1,2:3,4-di-O-isopropylidene-7-[[(1S)-1-phenylethyl] amino] L-glycero-alpha-D-galacto-Octopyranuronate
     
   Frédéric Coutrot, Claude Grison, Philippe Coutrot, Loïc Toupet     
  Acta Cryst. 2001, E57, o519-o520.

■ Discrepancy Regarding the Dethreading of a DB24C8 Macrocycle through a Perfluorobutyl End in [2]Pseudorotaxanes
   
   M. Gauthier and F. Coutrot
   Eur. J. Org. Chem. 2022, e202101201

■ Weinreb Amide, Ketone and Amine as Potential and Competitive Secondary Molecular Stations for Dibenzo-24-Crown-8
   in [2]Rotaxane Molecular Shuttles
   
   M. Gauthier and F. Coutrot
   Chem. Eur. J. 2021, 27, 17576-17580
   Evaluated as a hot paper and featured by a Cover Picture

■ Post-Synthetic Macrocyclization of Rotaxane Building Blocks
   
   M. Gauthier, P. Waelès and F. Coutrot
   ChemPlusChem 2022, 87, e202100458

  featured by a frontispiece and a Cover picture

► 2021

■ Study of [2] and [3]Rotaxanes Obtained by Post-Synthetic Aminolysis of a Kinetically Stable Though Activated
   Carbonate-Containing Pseudorotaxane
   
   P. Waelès, M. Gauthier and F. Coutrot
   Eur. J. Org. Chem. 2022, e202101385

■ [3]Foldarotaxane-Mediated Synthesis of an Improbable [2]Rotaxane

V. Koehler, M. Gauthier, C. Yao, K. Fournel-Marotte, P. Waelès, B. Kauffmann, I. Huc, F. Coutrot and Y. Ferrand
Chem. Commun. 2022, 58, 8618-8621

featured by the inside front cover of the issue

Frédéric Coutrot

► 2023

■ An Interlocked Figure-of-Eight Molecular Shuttle
   
   M. Gauthier, K. Fournel-Marotte, C. Clavel, P. Waelès, P. Laurent and F. Coutrot
   Angew. Chem. Int. Ed. 2023, e202310643

   highlighted by D. Zhao and G. Yang in Synfacts 2023, 19, 1193

► 2024

■ A Foldaxane-based Supramolecular Muscle-Like Switch
   
   P. Waelès and F. Coutrot
   ChemistryOpen 2024, e202400076